• Cramp Aid: Relief Tincture (3 PERIODS)
  • can you make the zinc look more raw/organic and not have letters on it?
  • well lit, closeup photo of an open purse on a desk seen from above with a cobalt blue tincture bottle inside it
  • closeup photo of an herbal liquid being droppered out of a dropper onto a tongue, against a light blue background

Cramp Aid: Relief Tincture (3 PERIODS)

3-Period Supply for Fact-Acting Cramp Relief
THIS PRE-ORDER SHIPS IN OCTOBER

Period pain shouldn’t put life on pause. Unlike conventional painkillers that only mask discomfort, Cramp Aid goes deeper to address root causes with high-potency anti-inflammatories and antispasmodics. This powerful blend of herbs and nutrients comes in a fast-absorbing liquid extract for drug-free relief you can count on.
  • Organic herbs
  • Alcohol free
  • Gluten free
  • Vegan

Provides in-the-moment support for painful periods by:

  • Fighting pelvic inflammation
  • Calming uterine muscle spasms
  • Boosting blood oxygen flow to sore muscles
  • Helping reduce reliance on painkillers with side effects
  • Delivering synergistic aid for period cravings, bloating, headache, and more
See the clinical studies

Ozgoli et al (2009). Comparison of effects of ginger, mefenamic acid, and ibuprofen on pain in women with primary dysmenorrhea. Journal of alternative and complementary medicine (New York, N.Y.), 15(2), 129–132.

Daily et al. (2015). Efficacy of ginger for alleviating the symptoms of primary dysmenorrhea: a systematic review and meta-analysis of randomized clinical trials. Pain Medicine, 16(12), 2243-2255.

Jenabi, E. (2013). The effect of ginger for relieving of primary dysmenorrhoea. J Pak Med Assoc, 63(1), 8-10.

Kashefi et al. (2014). Comparison of the effect of ginger and zinc sulfate on primary dysmenorrhea: a placebo-controlled randomized trial. Pain Management Nursing, 15(4), 826-833.

Khayat et al. (2014). Effect of treatment with ginger on the severity of premenstrual syndrome symptoms. International Scholarly Research Notices, ISRN obstetrics and gynecology, 792708.

Rahnama et al. (2012). Effect of Zingiber officinale R. rhizomes (ginger) on pain relief in primary dysmenorrhea: a placebo randomized trial. BMC complementary and alternative medicine,12(1), 92.

Shirvani et al. (2015). The effect of mefenamic acid and ginger on pain relief in primary dysmenorrhea: a randomized clinical trial. Archives of gynecology and obstetrics, 291(6), 1277-1281.

Negi et al. (2021). Efficacy of Ginger in the Treatment of Primary Dysmenorrhea: A Systematic Review and Meta-analysis. Cureus, 13(3), e13743. 

Moshfeghinia et al. (2024). Ginger for Pain Management in Primary Dysmenorrhea: A Systematic Review and Meta-Analysis. Journal of integrative and complementary medicine, 30(11), 1016–1030. 

Chen et al. (2016). Efficacy of Oral Ginger (Zingiber officinale) for Dysmenorrhea: A Systematic Review and Meta-Analysis. Evidence-based complementary and alternative medicine : eCAM, 2016, 6295737. 

Inanmdar et al. (2016). Clinical efficacy of Trigonella foenum graecum (Fenugreek) and dry cupping therapy on intensity of pain in patients with primary dysmenorrhea. Chinese journal of integrative medicine, Advance online publication. 

Younesy et al. (2014). Effects of fenugreek seed on the severity and systemic symptoms of dysmenorrhea. Journal of reproduction & infertility, 15(1), 41–48.

Deepa et al (2018.) Clinical evaluation of Methika (Trigonella foenumgraecum Linn.) and Chandrasura (Lepidium sativum Linn.) on primary dysmenorrhea. Ayurpharm Int J Ayur Alli Sci., 7(1), 1-8.

Masoumi et al. (2018). Effects of fenugreek seeds on the severity and duration of pain in primary dysmenorrhea in the students at Hamadan University of Medical sciences, Iran (2016). The Iranian Journal of Obstetrics, Gynecology and Infertility, 21(4), 25-33.

Rao et al. (2015). Influence of a Specialized Trigonella foenum-graecum Seed Extract (Libifem), on Testosterone, Estradiol and Sexual Function in Healthy Menstruating Women, a Randomised Placebo Controlled Study. Phytotherapy research : PTR, 29(8), 1123–1130.

Swaroop et al. (2015). Efficacy of a Novel Fenugreek Seed Extract (Trigonella foenum-graecum, Furocyst) in Polycystic Ovary Syndrome (PCOS). International journal of medical sciences, 12(10), 825–831. 

Moini Jazani et al. (2019). A comprehensive review of clinical studies with herbal medicine on polycystic ovary syndrome (PCOS). Daru : Journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 27(2), 863–877. 

Chevassus et al. (2009). A fenugreek seed extract selectively reduces spontaneous fat consumption in healthy volunteers. European journal of clinical pharmacology, 65(12), 1175–1178. 

Askarpour et al. (2020). Effect of fenugreek supplementation on blood lipids and body weight: A systematic review and meta-analysis of randomized controlled trials. Journal of ethnopharmacology, 253, 112538.

Jayasankari et al. (2024.) Effect Of Fenugreek Seeds On Premenstrual Syndrome Among Adolescent Girls In A Selected Community, Puducherry District. International Journal of Creative Research Thoughts, 12(11).

Zekavat et al. (2015). A randomised controlled trial of oral zinc sulphate for primary dysmenorrhoea in adolescent females. Australian and New Zealand Journal of Obstetrics and Gynaecology, 55(4), 369-373.

Teimoori et al. (2016). The efficacy of zinc administration in the treatment of primary dysmenorrhea. Oman medical journal, 31(2), 107.

Eby, G. A. (2007). Zinc treatment prevents dysmenorrhea. Medical Hypotheses, 69(2), 297-30.

Kashefi et al. (2014). Comparison of the effect of ginger and zinc sulfate on primary dysmenorrhea: a placebo-controlled randomized trial. Pain Management Nursing,15(4), 826-833.

Javanmardi et al. (2016). The effects of Zinc Acetate capsule on the intensity of primary dysmenorrhea: a randomized double-blind placebo-controlled clinical trial. The Iranian Journal of Obstetrics, Gynecology and Infertility, 19(25), 1-7.

Sangestani et al. (2015). The positive effects of zinc supplements on the improvement of primary dysmenorrhea and premenstrual symptoms: a double-blind, randomized, controlled trial. Journal of Midwifery and Reproductive Health, 3(3), 378-384.

Fathizadeh et al. (2016). Comparison of serum zinc concentrations and body antioxidant status between young women with premenstrual syndrome and normal controls: A case-control study. International Journal of Reproductive BioMedicine,14(11), 699.

Jafari et al. (2020). Effect of Zinc Supplementation on Physical and Psychological Symptoms, Biomarkers of Inflammation, Oxidative Stress, and Brain-Derived Neurotrophic Factor in Young Women with Premenstrual Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial. Biological trace element research, 194(1), 89–95.

Jafari et al. (2020). Effect of zinc supplementation on quality of life and sleep quality in young women with premenstrual syndrome: a randomized, double-blind, placebo-controlled trial. Archives of gynecology and obstetrics, 302(3), 657–664.

Siahbazi et al. (2017). Effect of zinc sulfate supplementation on premenstrual syndrome and health‐related quality of life: Clinical randomized controlled trial. Journal of Obstetrics and Gynaecology Research, 43(5), 887-894.

Ahmadi et al. (2023). The Effect of Zinc Supplementation on the Improvement of Premenstrual Symptoms in Female University Students: a Randomized Clinical Trial Study. Biological trace element research, 201(2), 559–566. 

Haider et al. (2025). A systematic review and meta-analysis examining the role of zinc supplementation in ameliorating physical and psychological manifestations of premenstrual syndrome in young females. European journal of obstetrics, gynecology, and reproductive biology, 312, 114082.

Chuong, C. J., & Dawson, E. B. (1994). Zinc and copper levels in premenstrual syndrome. Fertility and sterility, 62(2), 313-320.

Posaci, C., Erten, O., Üren, A., & Acar, B. (1994). Plasma copper, zinc and magnesium levels in patients with premenstrual tension syndrome. Acta obstetricia et gynecologica Scandinavica, 73(6), 452-455.

Dai et al. (2014). Effect of Jingqian Zhitong Fang on serum sex hormone levels in women with primary dysmenorrhea. Evidence-Based Complementary and Alternative Medicine, 876431.

Du et al. (2014). "Whole Chinese angelica" microemulsion: its preparation and in vivo and in vitro evaluations. Drug development and industrial pharmacy, 40(10), 1330–1339.

Seo et al. (2020). Dangguijagyag-san for primary dysmenorrhea: A PRISMA-compliant systematic review and meta-analysis of randomized-controlled trials. Medicine (Baltimore), 99(42): e22761.

Abdollahifard et al. (2014). The effects of vitamin B1 on ameliorating the premenstrual syndrome symptoms. Global journal of health science, 6(6), 144–153. 

Azadimoghtader, M. (2016). Effect of Vitamine B1 on the intensity primary dysmenorrheal. Preventive Care in Nursing & Midwifery Journal, 6(1), 1-7.

Gokhale, L. B. (1996). Curative treatment of primary (spasmodic) dysmenorrhoea. The Indian journal of medical research, 103, 227-231.

Hosseinlou et al. (2014). Effects of fish oil capsules and vitamin B1 tablets on duration and severity of dysmenorrhea in students of high school in Urmia-Iran. Global journal of health science, 6(7), 124.

Nayeban et al. (2014). A Comparison of the Effects of Vitamin E and Vitamin B1 on the Severity and Duration of Pain in Primary Dysmenorrhea. Journal of Midwifery and Reproductive Health, 2(2), 143-146.

Tofighi Niaki et al. (2012). Comparison of the effect of Vitamin B1 and Acupuncture on Treatment of Primary Dysmenorrhea. ISCA Journal of Biological Sciences,1(1), 62-6.

Zafari et al. (2011). Comparing the effect of vitamin B1 (vit. B1) and ibuprofen on the treatment of primary dysmenorrhea. African Journal of Pharmacy and Pharmacology, 5(7), 874-878.

Zamani, M., & Soltan, B. F. (2001). Evaluation the treatment effect of vitamin B1 in primary dysmenorrhea. Journal of Arak University of Medical Sciences, 4(3), 1-7.
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Why De Lune?

  • We formulate for acute relief
  • We formulate for long-term health
  • Natural ingredients, no nasty fillers
  • Safe to take with or without birth control
  • Science behind every single choice
  • Made by and for people with periods