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  • closeup photo of an herbal liquid being droppered out of a dropper onto a tongue, against a light blue background
  • well lit photo of ashwagandha root, cinnamon sticks, turmeric root, orange slices, and vanilla pod and flowers in a flat lay, like they are naturally strewn across a marble surface
  • photo of a cobalt blue glass tincture bottle by a bedside in a well lit bedroom with plant in bg

Endocrine Reset: Balancing Tincture

3-Cycle Supply for Daily Hormone Optimization
THIS PRE-ORDER SHIPS IN OCTOBER

Your hormonal balance is unique to you. That’s why products that directly tamper with estrogen and progesterone levels—yet market themselves as “balancing”—can actually make things worse. Holistic endocrine system support is the safe way to help your body find its unique balance, naturally. So if you’re struggling with symptoms or simply want to optimize your hormones, START HERE. 
  • Organic herbs
  • Alcohol free
  • Gluten free
  • Vegan

Supports your body's natural balance of estrogen, progesterone, and testosterone by:

  • Promoting a resilient, balanced stress response
  • Boosting an efficient metabolism to clear excess hormones
  • Providing essential vitamins for ovarian health
  • Supporting optimal liver function
  • Protecting from blood sugar spikes
See the clinical studies

Salve et al. (2019). Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study. Cureus, 11(12), e6466.

Auddy,  et al. (2008). A Standardized Withania Somnifera Extract Significantly Reduces Stress-Related Parameters in Chronically Stressed Humans: A Double-Blind, Randomized, Placebo-Controlled Study.

Dongre et al. (2015). Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Improving Sexual Function in Women: A Pilot Study. BioMed research international, 2015, 284154. 

Pingali et al. (2014). Effect of standardized aqueous extract of Withania somnifera on tests of cognitive and psychomotor performance in healthy human participants. Pharmacognosy research, 6(1), 12–18.

Choudhary et al. (2017). Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions. Journal of dietary supplements, 14(6), 599–612. 

Langade et al. (2019). Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study. Cureus, 11(9), e5797. 

Cheah et al. (2021). Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis. PloS one, 16(9), e0257843.

Akhgarjand et al. (2022). Does Ashwagandha supplementation have a beneficial effect on the management of anxiety and stress? A systematic review and meta-analysis of randomized controlled trials. Phytotherapy research : PTR, 36(11), 4115–4124.

Chandrasekhar et al (2012). A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian journal of psychological medicine, 34(3), 255–262.

Choudhary et al. (2017). Body Weight Management in Adults Under Chronic Stress Through Treatment With Ashwagandha Root Extract: A Double-Blind, Randomized, Placebo-Controlled Trial. Journal of evidence-based complementary & alternative medicine, 22(1), 96–106. 

Dehzad et al (2023). Effects of curcumin/turmeric supplementation on liver function in adults: A GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials. Complementary therapies in medicine, 74, 102952. 

Khayat et al (2015). Curcumin attenuates severity of premenstrual syndrome symptoms: A randomized, double-blind, placebo-controlled trial. Complementary therapies in medicine, 23(3), 318–324. 

DiSilvestro et al (2012). Diverse effects of a low dose supplement of lipidated curcumin in healthy middle aged people. Nutrition journal, 11, 79. 

Thota et al. (2018). Curcumin alleviates postprandial glycaemic response in healthy subjects: A cross-over, randomized controlled study. Scientific reports, 8(1), 13679. 

Heshmati et al. (2021). The effect of cinnamon supplementation on glycemic control in women with polycystic ovary syndrome: A systematic review and meta-analysis. Journal of food biochemistry, 45(1), e13543. 

Sarmadi et al. (2023). The effect of cinnamon consumption on lipid profile, oxidative stress, and inflammation biomarkers in adults: An umbrella meta-analysis of randomized controlled trials. Nutrition, metabolism, and cardiovascular diseases : NMCD, 33(10), 1821–1835.

Maierean et al & Lipid and Blood Pressure Meta-analysis Collaboration (LBPMC) Group (2017). The effects of cinnamon supplementation on blood lipid concentrations: A systematic review and meta-analysis. Journal of clinical lipidology, 11(6), 1393–1406.

Fateh et al. (2024). Effects of Cinnamon Supplementation on Lipid Profile: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Clinical nutrition research, 13(1), 74–87.

Xu et al. (2020). Efficacy of herbal medicine (cinnamon/fennel/ginger) for primary dysmenorrhea: a systematic review and meta-analysis of randomized controlled trials. The Journal of international medical research, 48(6), 300060520936179.

Wierzbowska et al. (2024). Vitamins in Gynecologic Malignancies. Nutrients, 16(9), 1392. 

Vašková et al. (2023). The Importance of Natural Antioxidants in Female Reproduction. Antioxidants (Basel, Switzerland), 12(4), 907.

Luck et al. (1995). Ascorbic acid and fertility. Biology of reproduction, 52(2), 262–266. 

Agarwal et al. (2005). Role of oxidative stress in female reproduction. Reproductive biology and endocrinology : RB&E, 3, 28. 

Rivers J. M. (1975). Oral contraceptives and ascorbic acid. The American journal of clinical nutrition, 28(5), 550–554. 

Buhling et al. The effect of micronutrient supplements on female fertility. Current opinion in obstetrics & gynecology, 25(3), 173–180. 

Amini et al. (2021). The Effect of Combined Vitamin C and Vitamin E Supplementation on Oxidative Stress Markers in Women with Endometriosis: A Randomized, Triple-Blind Placebo-Controlled Clinical Trial. Pain research & management, 2021, 5529741.

  • can you make it in natural daylight?

    Ashwagandha, the key to cortisol control

    Ashwagandha works with the HPA axis, a complex endocrine system, to regulate cortisol levels. This powerful cortisol control can improve anxiety, libido, sleep quality, cognitive function, and body weight management - even under stress.
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  • closeup photo of turmeric root in bright daylight

    Tumeric, the golden detox champion

    Excess hormones can act as toxins in the body, which is why it's critical for the liver to metabolize them efficiently. Turmeric/curcumin has been studied extensively for its ability to significantly improve liver function.
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  • closeup photo of a cinnamon stick in bright daylight

    Cinnamon, the blood glucose lifeguard

    Blood sugar dysregulation (think sugar highs and post-meal crashes) is linked to insulin resistance, hormonal imbalance, diabetes, and even PCOS. Cinnamon saves the day by significantly reducing blood triglycerides and inflammation.
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  • closeup photo of a sliced orange in bright daylight

    Vitamin C, the ovarian essential

    Vitamin C, a crucial antioxidant for reproductive health, may improve ovulation, fertility, and estrogen + progesterone production. It is even associated with significant reductions in endometriosis pain and endometrial cancer risk.
    Go deeper

Why De Lune?

  • We formulate for acute relief
  • We formulate for long-term health
  • Natural ingredients, no nasty fillers
  • Safe to take with or without birth control
  • Science behind every single choice
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