Why It Works
Our team of medical experts distilled decades of clinical research to create an all-natural solution for period pain.
400mg Magnesium Citrate (100% DV)
Many studies recommend magnesium as a reliable treatment for managing period pain. For example, magnesium has demonstrated a therapeutic effect on cramping in both the lower abdominal and back. Research has also recommended magnesium as a promising treatment for preventing migraine headaches, which many people struggle with during their period.
6mg Thiamin Hydrochloride (400% DV)
Vitamin B1 plays a critical role in energy metabolism, the nervous system, and muscle contraction. Because period cramps are caused by muscular contractions in the uterus, many researchers recommend vitamin B1 to manage menstrual pain.
In a clinical trial involving over 550 women, vitamin B1 was found to be an effective treatment for painful periods, eliminating pain symptoms in 87% of people.
8mg Pyridoxal Phosphate (400% DV)
Vitamin B6 is involved in the formation of neurotransmitters—brain chemicals that carry messages throughout our body. This explains why vitamin B6 has been shown to alleviate mood-related PMS symptoms.
A review of nine studies, involving nearly 1,000 women, found that vitamin B6 is effective in reducing PMS symptoms, including breast pain and depression. Another study found that vitamin B6 significantly reduced a broad range of PMS symptoms, including moodiness, irritability, forgetfulness, bloating, and anxiety.
The type of vitamin B6 in De Lune (Pyridoxal 5’ phosphate, or PLP) is the ‘active’ form. Your body is ready to use it as is, no conversion needed. Skipping the conversion can help increase the amount of B6 that’s absorbed into your system.
60mcg Methylcobalamin (1,000% DV)
Vitamin B12 plays an important role in the formation of new red blood cells. Since women lose blood with each menstrual cycle, research recommends replenishing nutrients that help restore the blood supply.
Unlike most B12 supplements, the type of B12 in De Lune (methylcobalamin) is the ‘active’ form, meaning your body is ready to use it with no conversion needed. This can increase the amount of B12 that’s absorbed into your system.
18mg Ferrous Sulfate (100% DV)
Iron is an essential component of hemoglobin—the protein in red blood cells that helps blood carry oxygen around the body. Because iron is stored in the blood, women lose a considerable amount of iron during their period each month.
Ingesting enough of this vital mineral goes a long way in improving health and well-being. For example, one study found that fatigue was reduced by 50% in menstruating womenwho regularly take iron supplements.
The type of iron in De Lune (ferrous sulfate) is the most ‘bioavailable’ form—that is, your body’s able to absorb and use it the best.
15mg Zinc Gluconate (100% DV)
Zinc helps boost blood circulation in the uterus, preventing the area from being cut off from oxygen and becoming painful. Multiple studies have shown that supplementing with zinc decreases the duration and severity of period pain.
Researchers also hypothesize that zinc has antioxidant and anti-inflammatory actions in the uterus. The body doesn’t have a storage system for zinc, so it’s important to get enough of this important mineral on a regular basis.
150mcg Potassium Iodide (100% DV)
Iodine is highly concentrated in the ovaries and breast tissue. Not surprisingly, this mineral plays an important role in women’s health. Promising research suggests iodine can prevent several breast diseases and reduce breast pain and tenderness.
Motherwort is a member of the mint family. It’s been used in both traditional European and Chinese medicine for menstrual difficulties, especially abdominal cramping and reducing inflammation in the uterus.
Numerous studies have demonstrated motherwort’s powerful antioxidant activity. Motherwort also seems to ease muscle tension and anxiety. A recent study concluded that motherwort has anti-anxiety effects comparable to common anti-anxiety drugs.
For centuries, dong quai has been widely used as a remedy for women’s health issues.
Researchers have identified a number of compounds in don quai that can promote antispasmodic activity. These compounds are thought to relieve menstrual cramping by relaxing the uterine muscles. Dong quai has also shown an ability to regulate the menstrual cycle and alleviate mood swings associated with PMS.
Research suggests that cramp bark acts as a relaxant to the uterus and lower back due to its natural phytochemicals: scopoletin and viopudial.
Studies have found that scopoletin is powerful enough to stop even electrically-induced muscle spasms. Viopudial works on the cellular level by blocking enzymes that create muscle cramps.
The anti-inflammatory properties of ginger have been valued for centuries.
Research shows that ginger can inhibit the formation of prostaglandins—tiny compounds that are released into the uterus during menstruation, causing the uterus to contract and become painful.
Multiple studies even concluded it was as effective as conventional painkillers like ibuprofen, but without the side effects. Ginger is also widely used to treat nausea, which many women struggle with during their period.
Dating back to 4000 BC, fenugreek is one of the oldest known herbal medicines. The ancient Egyptians are said to be the first to use it to treat menstrual cramping.
Studies show that fenugreek has antioxidant and anti-inflammatory properties. This may be why researchers find it effective for reducing period pain. In one study, women receiving a fenugreek supplement experienced reductions in symptoms like fatigue, nausea, headache, mood swings, and lack of energy.
1. Journal of American Science
2. International Journal of Pharmacy & Pharmaceutical Sciences
3. Journal of Food Chemistry
4. Chinese Journal of Integrative Medicine
5. Journal of Reproduction & Infertility
Apple Cider Vinegar
We use apple cider vinegar to brew our herbal blend. In fact, we’re one of the first supplements on the market to do so. We chose it as an all-natural way to prevent the growth of harmful bacterial without using chemical preservatives.
Apple cider vinegar has been used as a medicinal folk remedy for millennia. It contains a host of ‘polyphenols’—bioactive substances that act as antioxidants in the body. It’s also been reported to help protect the heart by lowering cholesterol.